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The selected dose of 120 mg/kg body weight is a well-established one for inducing significant and consistent testicular oxidative stress and spermatotoxicity in rodent models, as extensively documented in the literature 39

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Schneider M, Forster H, Boersma A, Seiler A, Wehnes H, Sinowatz F et al

A weak significant association between these levels and the warfarin sensitivity index suggests an interaction [309] (Table 2)

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